Difference between revisions of "Part:BBa K3346003:Design"

 
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===Design Notes===
 
===Design Notes===
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This BioBrick was designed for efficient expression in E. coli SHuffle. The constant region is mutated for better Fc receptor binding.
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This BioBrick was designed for efficient expression in E. coli SHuffle by performing codon optimization for an E. coli chassis using Reverse Translate Software available on The Sequence Manipulation Site. The constant region is mutated for better Fc receptor binding.
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Revision as of 21:20, 23 October 2020


Siltuximab Full Length IgG


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

This BioBrick was designed for efficient expression in E. coli SHuffle by performing codon optimization for an E. coli chassis using Reverse Translate Software available on The Sequence Manipulation Site. The constant region is mutated for better Fc receptor binding.


Source

The sequences in this part were found on UniProt database and DrugBank database.

References