Difference between revisions of "Part:BBa K3561023"

Revision as of 14:05, 11 October 2020

W3W4SVTQNKY

This peptide is expected to be a palladium reducing peptide. This peptide is modified by our team from the palladium reducing peptide SVTQNKY(Chiu et al., 2010). We have incorporated a tryptophan residue into the peptide as it was reported that tryptophan is capable of reducing palladium (Chiu et al., 2010). We implemented a double tryptophan structure at residues 3 and 4 as it was said that a double tryptophan is more effective than a single tryptophan structure in gold(Tan et al., 2010). We would like to investigate whether a double tryptophan will be more effective in palladium. We also want to investigate what effects will there have if we inserted the tryptophan residue at different positions.

This peptide has an isoelectric point of 9.7, a molecular weight of 0.98 kDa and hydrophobicity of 27.24. The serine residue at position 1 is reported to be important in binding with palladium(Chiu et al., 2010). The tryptophan residue at positions 3 and 4 are reported to reduce palladium(Chiu et al., 2010). The amino acid sequence of the peptide is SVWWNKY.

References

Chiu, et al. Size-Controlled Synthesis of Pd Nanocrystals Using a Specific Multifunctional Peptide. 2010, pubmed.ncbi.nlm.nih.gov/20648291/.

DI;, Tan YN;Lee JY;Wang. Uncovering the Design Rules for Peptide Synthesis of Metal Nanoparticles. 2010, pubmed.ncbi.nlm.nih.gov/20355728/.

Sequence and Features