Difference between revisions of "Part:BBa K2989007"

 
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Competitive endogenous RNA (ceRNA) hypothesis describes a complex post-transcriptional regulatory network that includes lncRNA, mRNA, and other types of RNA. They act as natural miRNA sponges that inhibit the function of other RNA by competing for one or more miRNA binding sites. Ce-HBsAg-125 can competingly inhibit miR-HBsAg-125 to allow transcription of HBsAg. It, together with miR-HBsAg-125, helps to form a regulation system.
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Competitive endogenous RNA (ceRNA) hypothesis describes a complex post-transcriptional regulatory network that includes lncRNA, mRNA, and other types of RNA. They act as natural miRNA sponges that inhibit the function of other RNA by competing for one or more miRNA binding sites.
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===Usage===
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Ce-HBsAg-125 is located in the downstream region of the hulc promoter. After specific initiation in tumor cells, the downstream Ce-HBsAg-125 is expressed. Ce-HBsAg-125 can competingly inhibit miR-HBsAg-125 to allow transcription of HBsAg It, together with miR-HBsAg-125, helps to form a regulation system.
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===Usage and Biology===
 
  
 
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Revision as of 05:25, 18 October 2019


Ce-HBsAg-125

Competitive endogenous RNA (ceRNA) hypothesis describes a complex post-transcriptional regulatory network that includes lncRNA, mRNA, and other types of RNA. They act as natural miRNA sponges that inhibit the function of other RNA by competing for one or more miRNA binding sites.


Usage

Ce-HBsAg-125 is located in the downstream region of the hulc promoter. After specific initiation in tumor cells, the downstream Ce-HBsAg-125 is expressed. Ce-HBsAg-125 can competingly inhibit miR-HBsAg-125 to allow transcription of HBsAg It, together with miR-HBsAg-125, helps to form a regulation system.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]