Difference between revisions of "Part:BBa K2989006"

 
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Competitive endogenous RNA (ceRNA) hypothesis describes a complex post-transcriptional regulatory network that includes lncRNA, mRNA, and other types of RNA. They act as natural miRNA sponges that inhibit the function of other RNA by competing for one or more miRNA binding sites. Ce-HBsAg-95 can competingly inhibit miR-HBsAg-95 to allow transcription of HBsAg. It, together with miR-HBsAg-95, helps to form a regulation system.
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Competitive endogenous RNA (ceRNA) hypothesis describes a complex post-transcriptional regulatory network that includes lncRNA, mRNA, and other types of RNA. They act as natural miRNA sponges that inhibit the function of other RNA by competing for one or more miRNA binding sites.
  
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===Usage===
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===Usage and Biology===
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Ce-HBsAg-95 is located in the downstream region of the hulc promoter. After specific initiation in tumor cells, the downstream Ce-HBsAg-95 is expressed. Ce-HBsAg-95 can competingly inhibit miR-HBsAg-95 to allow transcription of HBsAg It, together with miR-HBsAg-95, helps to form a regulation system.
  
 
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Revision as of 05:23, 18 October 2019


Ce-HBsAg-95

Competitive endogenous RNA (ceRNA) hypothesis describes a complex post-transcriptional regulatory network that includes lncRNA, mRNA, and other types of RNA. They act as natural miRNA sponges that inhibit the function of other RNA by competing for one or more miRNA binding sites.

Usage

Ce-HBsAg-95 is located in the downstream region of the hulc promoter. After specific initiation in tumor cells, the downstream Ce-HBsAg-95 is expressed. Ce-HBsAg-95 can competingly inhibit miR-HBsAg-95 to allow transcription of HBsAg It, together with miR-HBsAg-95, helps to form a regulation system.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]