Difference between revisions of "Part:BBa K2989004"
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__NOTOC__ | __NOTOC__ | ||
<partinfo>BBa_K2989004 short</partinfo> | <partinfo>BBa_K2989004 short</partinfo> | ||
+ | MiRNAs are a class of evolutionarily highly conserved single-stranded, non-coding small RNAs that are about 18 to 25 nt long. This kind of RNAs play important roles in many endogenic processes. Mostly, it functions as a post-transcriptional regulator of gene expression, which usually results in the silence of target gene. This process is commonly known as gene silencing. | ||
− | + | ===Usage=== | |
− | + | Our miR-HBsAg-125 can function at the 125bp of "Trojan horse" fragment (92 amino acid length HBsAg fragment).,and therefore, leads to the silence of our "Trojan horse" fragment. In this case, we can ensure that "Trojan horse" fragment will not be expressed in target cells, since the gene will be silenced by our part. | |
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− | + | ||
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Revision as of 05:17, 18 October 2019
miR-HBsAg-125
MiRNAs are a class of evolutionarily highly conserved single-stranded, non-coding small RNAs that are about 18 to 25 nt long. This kind of RNAs play important roles in many endogenic processes. Mostly, it functions as a post-transcriptional regulator of gene expression, which usually results in the silence of target gene. This process is commonly known as gene silencing.
Usage
Our miR-HBsAg-125 can function at the 125bp of "Trojan horse" fragment (92 amino acid length HBsAg fragment).,and therefore, leads to the silence of our "Trojan horse" fragment. In this case, we can ensure that "Trojan horse" fragment will not be expressed in target cells, since the gene will be silenced by our part.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]