Difference between revisions of "Part:BBa K3117004"

Revision as of 19:11, 16 October 2019

((Glycine)x4-Serine)x4 Linker

The linker BBa_K3117004 consists of four repeats of four times Glycin and one time Serine. (Gly4Ser)4 linker is one of the most widely used flexible linker that can sustain the bioactivity of fusion proteins. It was used by 2019 FAU_Erlangen to create a bispecific antibody targeting GPA33 on colon cancer cells and CD3 on T cells.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

Revision as of 19:08, 16 October 2019 (view source) Lena Schorr (Talk \| contribs) ← Older edit		Revision as of 19:11, 16 October 2019 (view source) Lena Schorr (Talk \| contribs) Newer edit →
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	<partinfo>BBa_K3117004 short</partinfo>		<partinfo>BBa_K3117004 short</partinfo>

−	The linker ~~BBa_K3117000~~ consists of ~~for~~ repeats of four times Glycin and one time Serine. (Gly4Ser)4 linker is one of the most widely used flexible linker that can sustain the bioactivity of fusion proteins. It was used by 2019 FAU_Erlangen to create a bispecific antibody targeting GPA33 on colon cancer cells and CD3 on T cells.	+	The linker BBa_K3117004 consists of four repeats of four times Glycin and one time Serine. (Gly4Ser)4 linker is one of the most widely used flexible linker that can sustain the bioactivity of fusion proteins. It was used by 2019 FAU_Erlangen to create a bispecific antibody targeting GPA33 on colon cancer cells and CD3 on T cells.