Difference between revisions of "Part:BBa K3096015"
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<partinfo>BBa_K3096015 short</partinfo>
 
<partinfo>BBa_K3096015 short</partinfo>
  
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pVEC (peptide vascular endothelial-cadherin) is a cell-penetrating peptide, which transports proteins through coadministration. pVEC is derived from a segment of the transmembrane domain part of a murine vascular endothelial-cadherin protein, which is involved in cell-cell adhesion. Its ability to enter the cell can mostly be explained by the N-terminal stretch of hydrophobic amino acids, which interact with the plasma membrane.  
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pVEC (peptide vascular endothelial-cadherin) is a cell-penetrating peptide, which transports proteins through coadministration. It is derived from a segment of the transmembrane domain part of a murine vascular endothelial-cadherin protein, which is involved in cell-cell adhesion. Its ability to enter the cell can mostly be explained by the N-terminal stretch of hydrophobic amino acids, which interact with the plasma membrane.  
  
 
===Sequence and Features===
 
===Sequence and Features===

Revision as of 18:33, 15 October 2019

pVEC - a cell penetrating peptide

pVEC (peptide vascular endothelial-cadherin) is a cell-penetrating peptide, which transports proteins through coadministration. It is derived from a segment of the transmembrane domain part of a murine vascular endothelial-cadherin protein, which is involved in cell-cell adhesion. Its ability to enter the cell can mostly be explained by the N-terminal stretch of hydrophobic amino acids, which interact with the plasma membrane.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


References

  1. Kamei, Noriyasu, et al. "Usefulness of cell-penetrating peptides to improve intestinal insulin absorption." Journal of Controlled Release 132.1 (2008): 21-25.
  2. Elmquist, Anna, Mats Hansen, and Ülo Langel. "Structure–activity relationship study of the cell-penetrating peptide pVEC." Biochimica et Biophysica Acta (BBA)-Biomembranes 1758.6 (2006): 721-729.