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<p>Lysosomal associated membrane protein 2 (Lamp 2) is a member of a family of membrane glycoproteins, which is highly expressed on the surface of exosomes. Much research has indicated that peptides fused to the N terminus of Lamp2 could be effectively displayed on the outer surface of exosomes. In 2019 CPU_CHINA project, we display PD-L1 targeting peptide on outer surface of exosomes and adopt this targeting exosome system to deliver hsa-let-7f into Mtb-infected macrophages specifically. | <p>Lysosomal associated membrane protein 2 (Lamp 2) is a member of a family of membrane glycoproteins, which is highly expressed on the surface of exosomes. Much research has indicated that peptides fused to the N terminus of Lamp2 could be effectively displayed on the outer surface of exosomes. In 2019 CPU_CHINA project, we display PD-L1 targeting peptide on outer surface of exosomes and adopt this targeting exosome system to deliver hsa-let-7f into Mtb-infected macrophages specifically. | ||
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Revision as of 02:12, 5 September 2019
Lamp 2
Usage and Biology
Lysosomal associated membrane protein 2 (Lamp 2) is a member of a family of membrane glycoproteins, which is highly expressed on the surface of exosomes. Much research has indicated that peptides fused to the N terminus of Lamp2 could be effectively displayed on the outer surface of exosomes. In 2019 CPU_CHINA project, we display PD-L1 targeting peptide on outer surface of exosomes and adopt this targeting exosome system to deliver hsa-let-7f into Mtb-infected macrophages specifically.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]