Difference between revisions of "Part:BBa K2933001"
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===References===
 
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===Expression and purification===
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===Enzymatic determination===
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===Hydrolysis efficiency of different antibiotics===

Revision as of 12:56, 3 September 2019


subclass B1 metallo-beta-lactamase NDM-23, codon optimized in E. coli

NDM-23 is a type of subclass B metal beta-lactamases, which is derived from NDM-1 mutation. The beta lactamases of the NDM family can hydrolyze almost all available beta lactam antibiotics (except aztreonam) clinically, including the broad-spectrum antibiotic carbapenems. Because of the extensive substrate profile of this enzyme, the clinical strains carrying it become a great threat to human life and health.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Usage and Biology

References

Expression and purification

Enzymatic determination

Hydrolysis efficiency of different antibiotics