Difference between revisions of "Part:BBa K3182007"
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Lactobacillus plantarum antibacterial peptide. Designed to target bacteria. This part was designed to be assembled with BBa_K3182100. | Lactobacillus plantarum antibacterial peptide. Designed to target bacteria. This part was designed to be assembled with BBa_K3182100. | ||
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| + | [[File:T--Linkoping_Sweden--MechofAction.png|650px|thumb|center|<b>Figure 1.</b> General mechanism of action when the antimicrobial agent is fused to BBa_K3182010 which contains the linker, thrombin site and cellulose binding domain. The cellulose binding domain enables the attachment of antimicrobial agents (such as antimicrobial peptide or enzyme) to the cellulose. This also inactivates the agents when they are expressed in its bacterial host. Later, when the bandage comes in contact with thrombin in the blood, the antimicrobial agents will be activated upon cleavage of its thrombin site.]] | ||
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Revision as of 15:06, 15 July 2019
Pln1
Lactobacillus plantarum antibacterial peptide. Designed to target bacteria. This part was designed to be assembled with BBa_K3182100.
Figure 1. General mechanism of action when the antimicrobial agent is fused to BBa_K3182010 which contains the linker, thrombin site and cellulose binding domain. The cellulose binding domain enables the attachment of antimicrobial agents (such as antimicrobial peptide or enzyme) to the cellulose. This also inactivates the agents when they are expressed in its bacterial host. Later, when the bandage comes in contact with thrombin in the blood, the antimicrobial agents will be activated upon cleavage of its thrombin site.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 68
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]