Difference between revisions of "Part:BBa K2765021"

Revision as of 20:11, 17 October 2018

yno1

Yno1(also known as aim14，short for Altered Inheritance rate of Mitochondria or ygl160w) encodes a genuine NADPH oxidase (NOX enzymes), which is located in the endoplasmic reticulum (ER) and produces superoxide in a NADPH-dependent fashion. Experiments have shown that overexpress yno1 can increase the accumulation of intracellular ROS.

reference: https://www.yeastgenome.org/locus/S000003128

Fig.2 overexpress yno1

T--BIT-China--PartRegulator_yno1_Fig3_process_of_Electron_transformation.png

Fig. 3 process of Electron transformation

Overexpression yno1 gene can causes MCA1 dependent apoptosis; likely involved in superoxide-mediated regulation of the actin cytoskeleton; member of a conserved superfamily of NADPH oxidases (NOX enzymes); has similarity to iron/copper reductases (FRE1-8), particularly Fre8p

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
INCOMPATIBLE WITH RFC[1000]
Illegal SapI.rc site found at 1569

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 <partinfo>BBa_K2765021 short</partinfo>
-Yon1(also known as aim14，short for Altered Inheritance rate of Mitochondria or ygl160w) encodes a genuine NADPH oxidase (NOX enzymes), which is located in the endoplasmic reticulum (ER) and produces superoxide in a NADPH-dependent fashion. Experiments have shown that overexpress yno1 can increase the accumulation of intracellular ROS.
+Yno1(also known as aim14，short for Altered Inheritance rate of Mitochondria or ygl160w) encodes a genuine NADPH oxidase (NOX enzymes), which is located in the endoplasmic reticulum (ER) and produces superoxide in a NADPH-dependent fashion. Experiments have shown that overexpress yno1 can increase the accumulation of intracellular ROS.
 https://static.igem.org/mediawiki/2018/c/c8/T--BIT-China--PartRegulator_yno1_Fig1_Position.png