Difference between revisions of "Part:BBa K2623002"
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===KaiB's function in KaiC's phosphorylation stage=== | ===KaiB's function in KaiC's phosphorylation stage=== | ||
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| − | [[Image:Kai_1_.gif|thumb|900px|Fig.2 Simplified scheme of the central circadian oscillator system.]]</th><th></table> | + | [[Image:Kai_1_.gif|thumb|900px|Fig.2 Simplified scheme of the central circadian oscillator system.[1]]]</th><th></table> |
| + | ===Reference=== | ||
| + | [1]Paddock, Mark, Boyd, et al. Active Output State of the Synechococcus Kai Circadian Oscillator[J]. Pnas, 2014, 110(40):E3849-E3857. | ||
| + | |||
More information about our project can be found on our results page.http://2018.igem.org/Team:XMU-China/Results <br> | More information about our project can be found on our results page.http://2018.igem.org/Team:XMU-China/Results <br> | ||
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Latest revision as of 19:51, 17 October 2018
KaiB coding region
Summary
It is a component of the Kai circuit, which inhibits the activation of KaiA to active KaiC ’s autophosphorylation, thereby enabling KaiC to dephosphorylate itself.
Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead need the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC.
A separate fragment is 309bp.
Structure of KaiB
KaiB's function in KaiC's phosphorylation stage
Reference
[1]Paddock, Mark, Boyd, et al. Active Output State of the Synechococcus Kai Circadian Oscillator[J]. Pnas, 2014, 110(40):E3849-E3857.
More information about our project can be found on our results page.http://2018.igem.org/Team:XMU-China/Results
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]