Difference between revisions of "Part:BBa K2534001:Design"

 
 
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<partinfo>BBa_K2534001 short</partinfo>
 
<partinfo>BBa_K2534001 short</partinfo>
  
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miRNA-370 5p has been discovered to function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling.
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[http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] worked to do lentiviral transfection of that part into colorectal cancer cell line RKO to induce regulatory apoptosis as well as to investigate it's immune modulatory effect on TLR-9.
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[http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] have characterized this part considering it's apoptotic effect of RKO cell lines.
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For further information about demonstration of its apoptotic effect, please visit our results page
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http://2018.igem.org/Team:AFCM-Egypt/Demonstrate
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For further information about design of our parts, please visit our Parts & Design Page
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http://2018.igem.org/Team:AFCM-Egypt/Parts
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https://static.igem.org/mediawiki/parts/c/c1/Ch370afcm.png
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This part has been modeled structurally and prepared for docking studies.
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for more details please visit our modeling page
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http://2018.igem.org/Team:AFCM-Egypt/Model
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https://static.igem.org/mediawiki/2018/7/73/T--AFCM-Egypt--3rd_pic.png
 
<partinfo>BBa_K2534001 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K2534001 SequenceAndFeatures</partinfo>
  
  
 
===Design Notes===
 
===Design Notes===
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IDT
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===Design Notes===
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this part has been synthesized through IDT offer
  
  
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===Source===
 
===Source===
  
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IDT
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http://2018.igem.org/Team:AFCM-Egypt/Bioinformatics_Page_link
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−
===References===
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Latest revision as of 14:51, 17 October 2018


miRNA 370 3p

miRNA-370 5p has been discovered to function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling. [http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] worked to do lentiviral transfection of that part into colorectal cancer cell line RKO to induce regulatory apoptosis as well as to investigate it's immune modulatory effect on TLR-9. [http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] have characterized this part considering it's apoptotic effect of RKO cell lines.

For further information about demonstration of its apoptotic effect, please visit our results page http://2018.igem.org/Team:AFCM-Egypt/Demonstrate For further information about design of our parts, please visit our Parts & Design Page http://2018.igem.org/Team:AFCM-Egypt/Parts

Ch370afcm.png

This part has been modeled structurally and prepared for docking studies. for more details please visit our modeling page http://2018.igem.org/Team:AFCM-Egypt/Model

T--AFCM-Egypt--3rd_pic.png


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

Design Notes

this part has been synthesized through IDT offer


Source

http://2018.igem.org/Team:AFCM-Egypt/Bioinformatics_Page_link