Difference between revisions of "Part:BBa K2534001"

 
 
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<partinfo>BBa_K2534001 short</partinfo>
 
<partinfo>BBa_K2534001 short</partinfo>
  
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miRNA 370 3p
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miRNA 370-3p has been discovered to function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling.
 +
[http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] worked to do lentiviral transfection of that part into colorectal cancer cell line RKO to induce regulatory apoptosis as well as to investigate it's immune modulatory effect on TLR-9.
 +
[http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] have characterized this part considering it's apoptotic effect of RKO cell lines.
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For further information about demonstration of its apoptotic effect, please visit our results page
 +
http://2018.igem.org/Team:AFCM-Egypt/Demonstrate
 +
For further information about design of our parts, please visit our Parts & Design Page
 +
http://2018.igem.org/Team:AFCM-Egypt/Parts
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https://static.igem.org/mediawiki/parts/c/c1/Ch370afcm.png
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<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here

Latest revision as of 14:47, 17 October 2018


miRNA 370 3p

miRNA 370-3p has been discovered to function as tumor suppressors in colorectal cancer by independently suppressing EGFR and PI3K signalling. [http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] worked to do lentiviral transfection of that part into colorectal cancer cell line RKO to induce regulatory apoptosis as well as to investigate it's immune modulatory effect on TLR-9. [http://2018.igem.org/Team:AFCM-Egypt# Team:AFCM-Egypt 2018] have characterized this part considering it's apoptotic effect of RKO cell lines.

For further information about demonstration of its apoptotic effect, please visit our results page http://2018.igem.org/Team:AFCM-Egypt/Demonstrate For further information about design of our parts, please visit our Parts & Design Page http://2018.igem.org/Team:AFCM-Egypt/Parts

Ch370afcm.png


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]