Difference between revisions of "Part:BBa K2765021"
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reference: https://www.yeastgenome.org/locus/S000003128 | reference: https://www.yeastgenome.org/locus/S000003128 | ||
| + | https://static.igem.org/mediawiki/2018/8/88/T--BIT-China--PartRegulator_yno1_Fig2_Overexpress.png | ||
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| + | Fig.2 overexpress yno1 | ||
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| + | https://static.igem.org/mediawiki/2018/a/ae/T--BIT-China--PartRegulator_yno1_Fig3_process_of_Electron_transformation.png | ||
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| + | Fig. 3 process of Electron transformation | ||
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| + | Overexpression yno1 gene can causes MCA1 dependent apoptosis; likely involved in superoxide-mediated regulation of the actin cytoskeleton; member of a conserved superfamily of NADPH oxidases (NOX enzymes); has similarity to iron/copper reductases (FRE1-8), particularly Fre8p | ||
Revision as of 22:52, 16 October 2018
yno1
Yon1(also known as aim14，short for Altered Inheritance rate of Mitochondria or ygl160w) encodes a genuine NADPH oxidase (NOX enzymes), which is located in the endoplasmic reticulum (ER) and produces superoxide in a NADPH-dependent fashion. Experiments have shown that overexpress yno1 can increase the accumulation of intracellular ROS.
reference: https://www.yeastgenome.org/locus/S000003128
Fig.2 overexpress yno1
Fig. 3 process of Electron transformation
Overexpression yno1 gene can causes MCA1 dependent apoptosis; likely involved in superoxide-mediated regulation of the actin cytoskeleton; member of a conserved superfamily of NADPH oxidases (NOX enzymes); has similarity to iron/copper reductases (FRE1-8), particularly Fre8p
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 1569