Difference between revisions of "Part:BBa K2796028"
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metabolism by tuning up the citric acid cycle) as potential synthetic exosome production boosters. Combined expression of
 
metabolism by tuning up the citric acid cycle) as potential synthetic exosome production boosters. Combined expression of
 
these genes significantly increased exosome production.(Ryosuke Kojima et al. 2008)</li>
 
these genes significantly increased exosome production.(Ryosuke Kojima et al. 2008)</li>
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[[File:2018 LZU-CHINA vesicle attacker.png|600px|thumb|center|]]
 
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===Usage and Biology===
 
===Usage and Biology===

Revision as of 15:21, 15 October 2018


Exosome booster

  • Exosome booster refers to hSDC4-T2A-STEAP3-P2A-NadB.We identified STEAP3 (involved in exosomebiogenesis), syndecan-4(SDC4; supports budding of endosomal membranes to form multivesicular bodies), and a fragment of L-aspartate oxidase (NadB; possibly boosts cellular metabolism by tuning up the citric acid cycle) as potential synthetic exosome production boosters. Combined expression of these genes significantly increased exosome production.(Ryosuke Kojima et al. 2008)
    • 2018 LZU-CHINA vesicle attacker.png

    Sequence and Features


    Assembly Compatibility:
    • 10
      COMPATIBLE WITH RFC[10]
    • 12
      COMPATIBLE WITH RFC[12]
    • 21
      INCOMPATIBLE WITH RFC[21]
      Illegal BglII site found at 192
      Illegal BglII site found at 1777
    • 23
      COMPATIBLE WITH RFC[23]
    • 25
      INCOMPATIBLE WITH RFC[25]
      Illegal AgeI site found at 2657
      Illegal AgeI site found at 3277
    • 1000
      INCOMPATIBLE WITH RFC[1000]
      Illegal SapI site found at 1367