Difference between revisions of "Part:BBa K2623004"

Revision as of 02:15, 14 October 2018

SasA coding region

Summary

It is involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs.
As part of the Kai circuit, phosphorylated KaiC can phosphorylate SasA, allowing SasA to participate in the downstream signaling pathway as a histidine kinase. Phosphorylated SasA can phosphorylate RpaA which acts as a specific transcription factor to participate in the expression of related genes.
A separate fragment is 1164 bp.

Structure of SasA

Fig.1

SasA's function

Fig.2

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
INCOMPATIBLE WITH RFC[21]
Illegal BglII site found at 538
Illegal BglII site found at 607
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

@@ Line 2: / Line 2: @@
 __NOTOC__
 <partinfo>BBa_K2623004 short</partinfo>
-===SUMMARY===
+===Summary===
 It is involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs.<br>
 As part of the Kai circuit, phosphorylated KaiC can phosphorylate SasA, allowing SasA to participate in the downstream signaling pathway as a histidine kinase. Phosphorylated SasA can phosphorylate RpaA which acts as a specific transcription factor to participate in the expression of related genes.<br>
 A separate fragment is 1164 bp.<br>
 ===Structure of SasA===
 [[Image:SasA.png|thumb|500px|Fig.1]]<br>