Difference between revisions of "Part:BBa K2403002"

Revision as of 19:11, 1 November 2017

T7 promoter>RRE(Rev Response Element)

You can transport high molecular mRNA into cytoplasm if you can use this parts BBa_2403000. Rev protein binds to RRE(Rev Response Element).

This part contains the RRE (Rev Response Element) of HIV-1 along with a T7 promoter for RNA expression. Together with the HIV-1 Rev protein part (BBa_K2403000), it can be used to efficiently export target RNAs from the eukaryotic nucleus out into the cytoplasm. Details are summarized in this link.

Reference

[1] Ichiro Taniguchi, Naoto Mabuchi and Mutsuhito Ohno (2014) HIV-1 Rev protein specifies the viral RNA export pathway by suppressing TAP/NXF1 recruitment Nucleic Acids Research, 6645–665

Sequence and Features