Difference between revisions of "Part:BBa K2239012"
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<partinfo>BBa_K2239012 short</partinfo>
 
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7beta-HSDH (7beta-hydroxysteroid dehydrogenase) reduces steroids at C-7 position. It reduces the intermediate product 7-oxo-LAC (7-ketolithocholic acid) into UDCA, the final product, where the carbonyl at C-7 position becomes hydroxyl.
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7beta-HSDH(7beta-hydroxysteroid dehydrogenase) catalyzes the reduction of hydroxysteroids at C-7 position and back, as it converts NADPH to NDAP+ and back. It catalyzes the reduction of the intermediate product 7-oxo-LAC (7-ketolithocholic acid) into UDCA, the final product, where the carbonyl at C-7 position becomes hydroxyl.[1]
  
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===Usage and Biology===
 
  
 
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Revision as of 00:41, 1 November 2017


7beta-HSDH

7beta-HSDH(7beta-hydroxysteroid dehydrogenase) catalyzes the reduction of hydroxysteroids at C-7 position and back, as it converts NADPH to NDAP+ and back. It catalyzes the reduction of the intermediate product 7-oxo-LAC (7-ketolithocholic acid) into UDCA, the final product, where the carbonyl at C-7 position becomes hydroxyl.[1]


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 448
  • 1000
    COMPATIBLE WITH RFC[1000]