Difference between revisions of "Part:BBa K2475000"
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<partinfo>BBa_K2475000 short</partinfo> | <partinfo>BBa_K2475000 short</partinfo> | ||
− | The Sup35 prion domain (PrD) contains the first | + | The Sup35 prion domain (PrD) contains the first 137 amino acids of the Sup35 protein. This domain gives the Sup35 protein the ability to aggregate. By fusing it to other proteins this aggregation ability should be transferred to other proteins. PrD fused to other proteins should have minimal impact of the folding structure, however loss of function may occur in the prion state due to localization of the protein in an aggregate composed of proteins with this domain attached. |
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Revision as of 01:41, 30 October 2017
Sup 35 Prion Domain (PrD)
The Sup35 prion domain (PrD) contains the first 137 amino acids of the Sup35 protein. This domain gives the Sup35 protein the ability to aggregate. By fusing it to other proteins this aggregation ability should be transferred to other proteins. PrD fused to other proteins should have minimal impact of the folding structure, however loss of function may occur in the prion state due to localization of the protein in an aggregate composed of proteins with this domain attached.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]