Difference between revisions of "Part:BBa K2486100"
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+ | __NOTOC__ | ||
+ | <partinfo>BBa_K2486100 short</partinfo> | ||
+ | |||
+ | [theoretical part] [not assembled, not synthesized, not sent, not characterized] | ||
+ | |||
+ | |||
+ | Nanobody targeting Trypanosoma bursei, the cause of african sleeping sickness, transmitted by the Tse-Tse fly. | ||
+ | |||
+ | GenBank acession: AY263488 https://www.ncbi.nlm.nih.gov/nuccore/AY263488 | ||
+ | |||
+ | 1 Stijlemans B, Conrath K, Cortez-Retamozo V, Van Xong H, Wyns L, et al. Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm. J Biol Chem. 2004;279:1256–1261 | ||
+ | |||
+ | 2 Stijlemans B, Caljon G, Natesan SKA, et al. High Affinity Nanobodies against the Trypanosome brucei VSG Are Potent Trypanolytic Agents that Block Endocytosis. Parsons M, ed. PLoS Pathogens. 2011;7(6):e1002072. doi:10.1371/journal.ppat.1002072. | ||
+ | |||
+ | |||
+ | <!-- Add more about the biology of this part here | ||
+ | ===Usage and Biology=== | ||
+ | |||
+ | <!-- --> | ||
+ | <span class='h3bb'>Sequence and Features</span> | ||
+ | <partinfo>BBa_K2486100 SequenceAndFeatures</partinfo> | ||
+ | |||
+ | |||
+ | <!-- Uncomment this to enable Functional Parameter display | ||
+ | ===Functional Parameters=== | ||
+ | <partinfo>BBa_K2486010 parameters</partinfo> | ||
+ | <!-- --> |
Latest revision as of 17:06, 27 October 2017
Trypanolytic nanobody Nb_An05 (no stop codon)
[theoretical part] [not assembled, not synthesized, not sent, not characterized]
Nanobody targeting Trypanosoma bursei, the cause of african sleeping sickness, transmitted by the Tse-Tse fly.
GenBank acession: AY263488 https://www.ncbi.nlm.nih.gov/nuccore/AY263488
1 Stijlemans B, Conrath K, Cortez-Retamozo V, Van Xong H, Wyns L, et al. Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm. J Biol Chem. 2004;279:1256–1261
2 Stijlemans B, Caljon G, Natesan SKA, et al. High Affinity Nanobodies against the Trypanosome brucei VSG Are Potent Trypanolytic Agents that Block Endocytosis. Parsons M, ed. PLoS Pathogens. 2011;7(6):e1002072. doi:10.1371/journal.ppat.1002072.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI site found at 50