Difference between revisions of "Part:BBa K2368007"
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+ | __NOTOC__ | ||
+ | <h1>Introduction</h1> | ||
+ | <partinfo>BBa_K2368007 short</partinfo> | ||
+ | <p> This part consists of the promoter gal1/gal10, sweetness receptor T1R2 and the terminator CYC1. The promoter gal1/gal10 is a bi-directional galactose-inducible promoter, which requires two percent of galactose to induce twelve hours to elicit protein expression. T1R3 is the sweetness receptor of the human tonge cells belonging to C type G protein coupled receptor.</p> | ||
+ | https://static.igem.org/mediawiki/2017/a/aa/G2C-1.png | ||
+ | <p> Fig.1 The schematic diagram of Gal1/Gal10+T1R2+CYC1</p> | ||
+ | <h1>Design</h1> | ||
+ | <p> We construct the part by Overlap Extension PCR. The Gal1/Gal10 promoter and CYC1 terminator stem from the PESC-Ura plasmid. We synthesize T1R2 by oligonucleotide synthesis.</p> | ||
+ | <h1>Experiment</h1> | ||
+ | <p> This part is used to express the sweetness receptor T1R2 in our experiment.</p> | ||
+ | https://static.igem.org/mediawiki/2017/1/1f/G2C-2.png | ||
+ | <p> Fig.2 Electrophoresis of Gal1/Gal10+T1R2+CYC1</p> | ||
+ | |||
+ | <!-- Add more about the biology of this part here | ||
+ | ===Usage and Biology=== | ||
+ | |||
+ | <!-- --> | ||
+ | <h2>Sequence and Features</h2> | ||
+ | <partinfo>BBa_K2368007 SequenceAndFeatures</partinfo> | ||
+ | |||
+ | |||
+ | <!-- Uncomment this to enable Functional Parameter display | ||
+ | ===Functional Parameters=== | ||
+ | <partinfo>BBa_K2368007 arameters</partinfo> | ||
+ | <!-- --> |
Revision as of 03:26, 24 October 2017
Introduction
PGal 1/10-T1R2-CYC1t
This part consists of the promoter gal1/gal10, sweetness receptor T1R2 and the terminator CYC1. The promoter gal1/gal10 is a bi-directional galactose-inducible promoter, which requires two percent of galactose to induce twelve hours to elicit protein expression. T1R3 is the sweetness receptor of the human tonge cells belonging to C type G protein coupled receptor.
Fig.1 The schematic diagram of Gal1/Gal10+T1R2+CYC1
Design
We construct the part by Overlap Extension PCR. The Gal1/Gal10 promoter and CYC1 terminator stem from the PESC-Ura plasmid. We synthesize T1R2 by oligonucleotide synthesis.
Experiment
This part is used to express the sweetness receptor T1R2 in our experiment.
Fig.2 Electrophoresis of Gal1/Gal10+T1R2+CYC1
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 563
Illegal BglII site found at 2061
Illegal BglII site found at 2481
Illegal BglII site found at 2643
Illegal BamHI site found at 674 - 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 291
Illegal AgeI site found at 1572
Illegal AgeI site found at 2790 - 1000COMPATIBLE WITH RFC[1000]