Difference between revisions of "Part:BBa K2309000"
| Line 4: | Line 4: | ||
AgrC is a membrane-located protein, which can sense specifically mature group 1 autoinducing peptides (also known as AIPs, a kind of intracellular signal molecule) that are synthesized by Staphylococcus. When bound by AIPs, it then will change the conformation and gain the capability to phosphorylate protein AgrA, which can futher activate P2 promotor expression. | AgrC is a membrane-located protein, which can sense specifically mature group 1 autoinducing peptides (also known as AIPs, a kind of intracellular signal molecule) that are synthesized by Staphylococcus. When bound by AIPs, it then will change the conformation and gain the capability to phosphorylate protein AgrA, which can futher activate P2 promotor expression. | ||
| + | |||
| + | Wrong use of this group one agr regulation may lead to adverse experimental consequences. Appliction of AIP-II and AIP-IV into this sensing system will cause inhibition of the agr-regulated expression. | ||
<!-- Add more about the biology of this part here | <!-- Add more about the biology of this part here | ||
Latest revision as of 09:52, 26 September 2017
AIP receptor
AgrC is a membrane-located protein, which can sense specifically mature group 1 autoinducing peptides (also known as AIPs, a kind of intracellular signal molecule) that are synthesized by Staphylococcus. When bound by AIPs, it then will change the conformation and gain the capability to phosphorylate protein AgrA, which can futher activate P2 promotor expression.
Wrong use of this group one agr regulation may lead to adverse experimental consequences. Appliction of AIP-II and AIP-IV into this sensing system will cause inhibition of the agr-regulated expression.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]