Difference between revisions of "Part:BBa K2217015"
 
Line 3: Line 3:
 
<partinfo>BBa_K2217015 short</partinfo>
 
<partinfo>BBa_K2217015 short</partinfo>
  
−
Poly (A) signal roles are definition of transcription end site, releasing newly synthesized RNA from transcription machinery, and promoting RNA half-life. In prokaryotes, it defines termination site by two manners including Rho-dependent/independent mechanisms. In mammalian expression plasmids, the poly (A) signal of SV40 is efficient terminator of transcription
+
The bovine growth hormone polyadenylation (bgh-PolyA) signal is a specialized termination sequence for protein expression in eukaryotic cells. This DNA sequence is useful for producing pharmaceutical proteins and peptides in culture, increasing gene expression in gene therapy and protein production in transgenic animals.
  
 
<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here

Latest revision as of 18:41, 23 September 2017


bGH poly(A) signal

The bovine growth hormone polyadenylation (bgh-PolyA) signal is a specialized termination sequence for protein expression in eukaryotic cells. This DNA sequence is useful for producing pharmaceutical proteins and peptides in culture, increasing gene expression in gene therapy and protein production in transgenic animals.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]