Difference between revisions of "Part:BBa K1898400"

 
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<partinfo>BBa_K1898400 short</partinfo>
 
<partinfo>BBa_K1898400 short</partinfo>
  
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This gene codes for cryab, or crystallin alpha B, a crystallin protein exists in the lens and also other tissues and organs.  
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This gene codes for cryab, also known as crystallin alpha B, a crystallin protein exists in the lens and also other tissues and organs.  
  
 
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===Usage and Biology===
 
===Usage and Biology===
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Alpha crystallin is the most abundant protein in the lens. Out of the two types of alpha crystallin proteins, alpha A is more restricted to the lens and has a 3:1 ratio to alpha B [1]. It has been found that crystallin alpha A has chaperone activity to maintain normal protein interaction [2].
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In our project, we made CRYAA because we wanted to monitor crystallin protein's response to oxidative stress and to test our prevention and treatment for cataracts.
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[1]Genes and mapped phenotypes. (n.d.). from https://www.ncbi.nlm.nih.gov/gene/1410
  
 
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Revision as of 18:18, 18 October 2016


CRYAB, crystallin alpha B

This gene codes for cryab, also known as crystallin alpha B, a crystallin protein exists in the lens and also other tissues and organs.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BamHI site found at 26
    Illegal BamHI site found at 368
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 453
    Illegal SapI.rc site found at 313