Difference between revisions of "Part:BBa K135000"

Latest revision as of 11:48, 15 October 2016

pCpxR (CpxR responsive promoter)

This is an adhesion responsive promoter (specifically adhesion to hydrophobic surfaces), and can be used to upregulate downstream gene expression in response to adhesion to such surfaces. It contains the binding site for CpxR-P (phosphorylated CpxR). CpxR is one member of the two-component Cpx response to envelope stress. Briefly, envelope stress causes CpxA, an inner-membrane histidine Kinase to Phosphorylate CpxR, allowing it to bind to CpxR-P responsive regions and regulate downstream target genes. See references for further information.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

Functional Parameters

negative_regulators	-NA-
positive_regulators	1

@@ Line 2: / Line 2: @@
 <partinfo>BBa_K135000 short</partinfo>
-Ths is an adhesion responsive promoter (specifically adhesion to hydrophobic surfaces), and can be used to upregulate downstream gene expression in response to adhesion to such surfaces. It contains the binding site for CpxR-P (phosphorylated CpxR). CpxR is one member of the two-component Cpx response to envelope stress. Briefly, envelope stress causes CpxA, an inner-membrane histidine Kinase to Phosphorylate CpxR, allowing it to bind to CpxR-P responsive regions and regulate downstream target genes. See [[Part:BBa_K135000:Design | references]] for further information.
+This is an adhesion responsive promoter (specifically adhesion to hydrophobic surfaces), and can be used to upregulate downstream gene expression in response to adhesion to such surfaces. It contains the binding site for CpxR-P (phosphorylated CpxR). CpxR is one member of the two-component Cpx response to envelope stress. Briefly, envelope stress causes CpxA, an inner-membrane histidine Kinase to Phosphorylate CpxR, allowing it to bind to CpxR-P responsive regions and regulate downstream target genes. See [[Part:BBa_K135000:Design | references]] for further information.
 <!-- Add more about the biology of this part here