Difference between revisions of "Part:BBa K1692020"

Revision as of 03:36, 20 September 2015

S. aureus type II PanK (CoaA)

This basic part is type II pantothenate kinase (panK) from Staphylococcus aureus, which means that it is not sensitive to feedback inhibition from coenzyme A or acetyl-CoA. This means that high levels of coenzyme A accumulate. We did not experiment with this gene alone; instead, we incorporated it into an already-existing biobrick (BBa_K1149051) to increase the production of poly-3-hydroxybuterate, a plastic of which coenzyme A is a precursor.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
INCOMPATIBLE WITH RFC[12]
Illegal NheI site found at 10
Illegal NheI site found at 33
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
INCOMPATIBLE WITH RFC[25]
Illegal AgeI site found at 420
1000
COMPATIBLE WITH RFC[1000]

@@ Line 1: / Line 1: @@
 __NOTOC__
 <partinfo>BBa_K1692020 short</partinfo>
-Type II pantothenate kinase from Staphylococcus aureus, not sensitive to feedback inhibition from CoA.
+This basic part is type II pantothenate kinase (panK) from <i>Staphylococcus aureus</i>, which means that it is not sensitive to feedback inhibition from coenzyme A or acetyl-CoA. This means that high levels of coenzyme A accumulate. We did not experiment with this gene alone; instead, we incorporated it into an already-existing biobrick (BBa_K1149051) to increase the production of poly-3-hydroxybuterate, a plastic of which coenzyme A is a precursor.
 <!-- Add more about the biology of this part here