Difference between revisions of "Part:BBa K1783004"

Latest revision as of 02:04, 19 September 2015

Epsilon Cyclase

A. thaliana LCYE (lycopene epsilon cyclase) with chloroplast transit peptide removed. Catalyzes the formation of one epsilon ring on lycopene. Does not act on delta-carotene or gamma-carotene.

Epsilon cyclase functions as an intermediate step in the conversion of lycopene to lutein, supplements of which delay the onset and lessen the symptoms of Age-Related Macular Degeneration. In concert with crtE, crtI, and crtB, which redirect the mevalonate pathway to produce lycopene, epsilon and beta cyclases and hydroxylases catalyze a series of four reactions to produce the two hydroxylated rings that differentiate lutein from lycopene.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
INCOMPATIBLE WITH RFC[21]
Illegal BamHI site found at 91
Illegal BamHI site found at 1398
23
COMPATIBLE WITH RFC[23]
25
INCOMPATIBLE WITH RFC[25]
Illegal NgoMIV site found at 223
Illegal AgeI site found at 1030
1000
INCOMPATIBLE WITH RFC[1000]
Illegal BsaI.rc site found at 1105

@@ Line 3: / Line 3: @@
 A. thaliana LCYE (lycopene epsilon cyclase) with chloroplast transit peptide removed. Catalyzes the formation of one epsilon ring on lycopene. Does not act on delta-carotene or gamma-carotene.
+Epsilon cyclase functions as an intermediate step in the conversion of lycopene to lutein, supplements of which delay the onset and lessen the symptoms of Age-Related Macular Degeneration. In concert with crtE, crtI, and crtB, which redirect the mevalonate pathway to produce lycopene, epsilon and beta cyclases and hydroxylases catalyze a series of four reactions to produce the two hydroxylated rings that differentiate lutein from lycopene.
 <!-- Add more about the biology of this part here