Difference between revisions of "Part:BBa K1745002"

Latest revision as of 19:49, 18 September 2015

AANAT Expression

Expression and possibly secretion of enzyme AANAT (aralkylamine N-acetyltransferase) [ Homo sapiens (human) ]. AANAT catalyzes Serotonin into N-acetylserotonin, a Melatonin precursor, and it is the rate-limiting step in Melatonin production. (Zheng 2002) Melatonin (N-acetyl-5-methoxytryptamine) is responsible for regulating circadian rhythms such as the sleep cycle and seasonal behaviors such as color change and reproduction in animals.(Lincoln 2003) In humans, AANAT is secreted in the Pineal gland. This construct is His-tagged.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
INCOMPATIBLE WITH RFC[12]
Illegal NheI site found at 7
Illegal NheI site found at 30
21
INCOMPATIBLE WITH RFC[21]
Illegal BamHI site found at 115
23
COMPATIBLE WITH RFC[23]
25
INCOMPATIBLE WITH RFC[25]
Illegal NgoMIV site found at 509
1000
COMPATIBLE WITH RFC[1000]

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 __NOTOC__
 <partinfo>BBa_K1745002 short</partinfo>
-Expression and possibly secretion of enzyme AANAT (aralkylamine N-acetyltransferase) [ Homo sapiens (human) ]. AANAT catalyzes Serotonin into N-acetylserotonin, a Melatonin precursor, and it is the rate-limiting step in Melatonin production. (Zheng 2002) Melatonin (N-acetyl-5-methoxytryptamine) is resposible for regulating circadium rhythms such as the sleep cycle and seasonal behaviors such as color change and reproduction in animals.(Lincoln 2003) In humans, AANAT is secreted in the Pineal gland. This construct is His-tagged.
+Expression and possibly secretion of enzyme AANAT (aralkylamine N-acetyltransferase) [ Homo sapiens (human) ]. AANAT catalyzes Serotonin into N-acetylserotonin, a Melatonin precursor, and it is the rate-limiting step in Melatonin production. (Zheng 2002) Melatonin (N-acetyl-5-methoxytryptamine) is responsible for regulating circadian rhythms such as the sleep cycle and seasonal behaviors such as color change and reproduction in animals.(Lincoln 2003) In humans, AANAT is secreted in the Pineal gland. This construct is His-tagged.
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