Difference between revisions of "Part:BBa K1813004"

 
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<partinfo>BBa_K1813004 short</partinfo>
 
<partinfo>BBa_K1813004 short</partinfo>
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===Usage and Biology===
 
===Usage and Biology===
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CYP6G1 is a cytochrome p450 enzyme from <i>Drosophila melanogaste </i> capable of hydroxylating imidacloprid at the 4 and carbons.
 
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<span class='h3bb'>Sequence and Features</span>
 
<span class='h3bb'>Sequence and Features</span>
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<h2>Background of <i>CYP6G1</i></h2>
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As an enzyme capable of hydroxylating the 4 and 5 carbons of imidacloprid, it is capable of bestowing a significant protective effect to insects harboring this gene. It has an affinity to 6OH imidacloprid, allowing it to gnerate 4,5 OH imidacloprid, which has an ld50 of over 1 microgram vs 30 nanograms for imidacloprid. Used in conjunction with CYP6CM1vQ,  (BBa_K1813003) it can be extremely effective in bestowing imidacloprid resistance to an organism.

Revision as of 02:40, 18 September 2015

CYP6G1

CYP6G1

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 934
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI.rc site found at 943


Background of CYP6G1

As an enzyme capable of hydroxylating the 4 and 5 carbons of imidacloprid, it is capable of bestowing a significant protective effect to insects harboring this gene. It has an affinity to 6OH imidacloprid, allowing it to gnerate 4,5 OH imidacloprid, which has an ld50 of over 1 microgram vs 30 nanograms for imidacloprid. Used in conjunction with CYP6CM1vQ, (BBa_K1813003) it can be extremely effective in bestowing imidacloprid resistance to an organism.