Difference between revisions of "Part:BBa K1769000"
| Line 1: | Line 1: | ||
| − | |||
__NOTOC__ | __NOTOC__ | ||
<partinfo>BBa_K1769000 short</partinfo> | <partinfo>BBa_K1769000 short</partinfo> | ||
| Line 7: | Line 6: | ||
<!-- Add more about the biology of this part here | <!-- Add more about the biology of this part here | ||
===Usage and Biology=== | ===Usage and Biology=== | ||
| + | Many pathogen, such as <i>Plasmodium falciparum<i> that causes malaria and | ||
| + | <i>Phytophthora<i> spp. that cause a wide range of plant disaeses,inhibits the immune system of host cell by secreting effector proteins. These effector protein translocate into host cell by binding to a outer membrane receptor, PI3P. This biobrick can not only serve as a useful tool to study the signal transduction pathway of PI3P but can also be a weapon to stop these pathogen's infection. | ||
<!-- --> | <!-- --> | ||
Revision as of 00:24, 17 September 2015
Dimeric FYVE
Dimeric Hrs FYVE is a small binding molecule that can bind to phosphatidylinositol 3-phosphate (PtdIns(3)P), a receptor that exists on endosome. Since it is more stable then monomeric FYVE, it is widely used to recognize and locate PtdIns(3)P.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 110
Illegal BglII site found at 329 - 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]