Difference between revisions of "Part:BBa K1230000"
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Team iGEM Nagahama 2015 | Team iGEM Nagahama 2015 | ||
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| − | We improved the characterization of a previously existing BioBrick Part [https://parts.igem.org/Part:BBa_K1230000 BBa_K1230000] and submitted this improved BioBrick ''marA'' | + | We improved the characterization of a previously existing BioBrick Part [https://parts.igem.org/Part:BBa_K1230000 BBa_K1230000] and submitted this improved BioBrick ''marA'' gene as [https://parts.igem.org/wiki/index.php?title=Part:BBa_K1653006 BBa_K1653006] to iGEM Registry. |
Revision as of 06:38, 16 September 2015
AcrAB-TolC multidrug efflux transport system activator from E. coli
The MarA protein acts as a transcriptional activator in E. coli, it allows the expression of the acrAB and tolC operons, which activate the AcrAB-TolC efflux pump, a mechanism that has been related with resistance to organic solvents, dyes, detergents, antibiotics such as chloramphenicol, tetracycline, novobiocin, erythromycin, fusidic acid and cloxacillin, as well as to cationic antimicrobial peptides, such as LL-37, HNP-2 and HBD-1.
We used device BBa_K1230004 to characterise this part.
Team iGEM Nagahama 2015
We improved the characterization of a previously existing BioBrick Part BBa_K1230000 and submitted this improved BioBrick marA gene as BBa_K1653006 to iGEM Registry.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 154
- 1000COMPATIBLE WITH RFC[1000]