Difference between revisions of "Part:BBa K1391012"

Revision as of 02:15, 31 October 2014

pENTR_Cofilin (Inactivated - pseudophosphorylated)

Cofilin is an actin depolymerizing factor. It is recruited when PirB/LilrB2 is activated by beta-amyloid. [1]

The 3rd amino acid in this construct has been mutated to make it pseudophophoralated and inactive. It was ordered from Adgene.

[1] Taeho Kim, George S. Vidal, Maya Djurisic, et al. "Human LilrB2 is a beta-amyloid recptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's Model". Science. 20 Sep 2013. <http://www.sciencemag.org/content/341/6152/1399>. 16 Oct 2014.

The characterization of the system this is part of can be found in the experience page.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
INCOMPATIBLE WITH RFC[1000]
Illegal BsaI.rc site found at 268
Illegal SapI site found at 108

@@ Line 1: / Line 1: @@
 __NOTOC__
 <partinfo>BBa_K1391012 short</partinfo>
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 [1] Taeho Kim, George S. Vidal, Maya Djurisic, et al. "Human LilrB2 is a beta-amyloid recptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's Model". Science. 20 Sep 2013. <http://www.sciencemag.org/content/341/6152/1399>. 16 Oct 2014.
+The characterization of the system this is part of can be found in the experience page.