Difference between revisions of "Part:BBa K1371039:Design"
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===Design Notes=== | ===Design Notes=== | ||
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===Source=== | ===Source=== | ||
− | + | <i>Saccharopolyspora erythraea</i> | |
===References=== | ===References=== | ||
+ | [1]Cane, David E. Programming of erythromycin biosynthesis by a modular polyketide synthase [J]. Journal of Biological Chemistry, 2010, 285.36: 27517-27523.<p></p> | ||
+ | [2]Komaki, Hisayuki, et al. Genome based analysis of type-I polyketide synthase and nonribosomal peptide synthetase gene clusters in seven strains of five representative Nocardia species [J]. BMC genomics 15.1 (2014): 323.<p></p> | ||
+ | [3]Pfeifer, Blaine A., et al. Biosynthesis of complex polyketides in a metabolically engineered strain of <i>E. coli</i> [J]. Science, 2001, 291.5509: 1790-1792.<p></p> | ||
+ | [4]Tae, Hongseok, Jae Kyung Sohng, and Kiejung Park. Development of an analysis program of type I polyketide synthase gene clusters using homology search and profile hidden Markov model [J]. Journal of microbiology and biotechnology, 2009, 19.2: 140-146.<p></p> | ||
+ | [5]Cortes, Jesus, et al. An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of <i>Saccharopolyspora erythraea</i> [J]. 1990: 176-178.<p></p> | ||
+ | [6]Khosla, Chaitan, Shiven Kapur, and David E. Cane. Revisiting the modularity of modular polyketide synthases [J]. Current opinion in chemical biology, 2009, 13.2: 135-143.<p></p> | ||
+ | [7]Menzella, Hugo G., et al. Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster [J]. Journal of Industrial Microbiology and Biotechnology,2006, 33.1: 22-28.<p></p> | ||
+ | [8]Oliynyk, Markiyan, et al. A hybrid modular polyketide synthase obtained by domain swapping [J]. Chemistry & biology,1996, 3.10: 833-839.<p></p> | ||
+ | [9]Lau, Janice, David E. Cane, and Chaitan Khosla. Substrate specificity of the loading didomain of the erythromycin polyketide synthase [J]. Biochemistry, 2000, 39.34: 10514-10520.<p></p> | ||
+ | [10]Nowak-Thompson, Brian, et al. Characterization of the pyoluteorin biosynthetic gene cluster of <i>Pseudomonas fluorescens</i> Pf-5 [J]. Journal of bacteriology, 1999, 181.7: 2166-2174.<p></p> | ||
+ | [11]Caffrey, Patrick, et al. Amphotericin biosynthesis in <i>Streptomyces nodosus</i> deductions from analysis of polyketide synthase and late genes [J]. Chemistry & biology,2001, 8.7: 713-723. [12]Dunn, Briana J., et al. Comparative analysis of the substrate specificity of trans-versus cis-acyltransferases of assembly line polyketide synthases [J]. Biochemistry,2014.<p></p> | ||
+ | [13]Jiang, Ming, and Blaine A. Pfeifer. Metabolic and pathway engineering to influence native and altered erythromycin production through <i>E. Coli</i> [J]. Metabolic engineering, 2013, 19: 42-49. [14]Chen, Xianzhong, et al. Metabolic engineering of <i>Escherichia coli</i>: A sustainable industrial platform for bio-based chemical production [J]. Biotechnology advances, 2013, 31.8: 1200-1223.<p></p> |
Latest revision as of 17:44, 24 October 2014
loading module+module(1+2)
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 1827
Illegal BamHI site found at 6372
Illegal BamHI site found at 9222 - 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 507
Illegal NgoMIV site found at 1990
Illegal NgoMIV site found at 2362
Illegal NgoMIV site found at 2395
Illegal NgoMIV site found at 2868
Illegal NgoMIV site found at 3577
Illegal NgoMIV site found at 4450
Illegal AgeI site found at 318
Illegal AgeI site found at 1680
Illegal AgeI site found at 2026
Illegal AgeI site found at 2605
Illegal AgeI site found at 4326
Illegal AgeI site found at 4396
Illegal AgeI site found at 5023 - 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 1432
Illegal BsaI.rc site found at 3862
Illegal SapI.rc site found at 2697
Design Notes
Source
Saccharopolyspora erythraea