Difference between revisions of "Part:BBa K1371037:Design"

Revision as of 20:21, 7 October 2014 (view source) Registry (Talk | contribs)		Latest revision as of 17:44, 24 October 2014 (view source) Invly leung (Talk | contribs)
Line 1:		Line 1:
−
	__NOTOC__		__NOTOC__
	<partinfo>BBa_K1371037 short</partinfo>		<partinfo>BBa_K1371037 short</partinfo>
Line 7:		Line 6:
	===Design Notes===		===Design Notes===
−	aa	+	<p></p>
−		+
−		+
−		+
	===Source===		===Source===
−	aa	+	<i>Saccharopolyspora erythraea</i>
	===References===		===References===
		+	[1]Cane, David E. Programming of erythromycin biosynthesis by a modular polyketide synthase [J]. Journal of Biological Chemistry, 2010, 285.36: 27517-27523.<p></p>
		+	[2]Komaki, Hisayuki, et al. Genome based analysis of type-I polyketide synthase and nonribosomal peptide synthetase gene clusters in seven strains of five representative Nocardia species [J]. BMC genomics 15.1 (2014): 323.<p></p>
		+	[3]Pfeifer, Blaine A., et al. Biosynthesis of complex polyketides in a metabolically engineered strain of <i>E. coli</i> [J]. Science, 2001,  291.5509: 1790-1792.<p></p>
		+	[4]Tae, Hongseok, Jae Kyung Sohng, and Kiejung Park. Development of an analysis program of type I polyketide synthase gene clusters using homology search and profile hidden Markov model [J]. Journal of microbiology and biotechnology, 2009, 19.2: 140-146.<p></p>
		+	[5]Cortes, Jesus, et al. An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of <i>Saccharopolyspora erythraea</i> [J]. 1990: 176-178.<p></p>
		+	[6]Khosla, Chaitan, Shiven Kapur, and David E. Cane. Revisiting the modularity of modular polyketide synthases [J]. Current opinion in chemical biology, 2009, 13.2: 135-143.<p></p>
		+	[7]Menzella, Hugo G., et al. Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster [J]. Journal of Industrial Microbiology and Biotechnology,2006, 33.1: 22-28.<p></p>
		+	[8]Oliynyk, Markiyan, et al. A hybrid modular polyketide synthase obtained by domain swapping [J]. Chemistry & biology,1996, 3.10: 833-839.<p></p>
		+	[9]Lau, Janice, David E. Cane, and Chaitan Khosla. Substrate specificity of the loading didomain of the erythromycin polyketide synthase [J]. Biochemistry, 2000, 39.34: 10514-10520.<p></p>
		+	[10]Nowak-Thompson, Brian, et al. Characterization of the pyoluteorin biosynthetic gene cluster of <i>Pseudomonas fluorescens</i> Pf-5 [J]. Journal of bacteriology, 1999, 181.7: 2166-2174.<p></p>
		+	[11]Caffrey, Patrick, et al. Amphotericin biosynthesis in <i>Streptomyces nodosus</i> deductions from analysis of polyketide synthase and late genes [J]. Chemistry & biology,2001, 8.7: 713-723. [12]Dunn, Briana J., et al. Comparative analysis of the substrate specificity of trans-versus cis-acyltransferases of assembly line polyketide synthases [J]. Biochemistry,2014.<p></p>
		+	[13]Jiang, Ming, and Blaine A. Pfeifer. Metabolic and pathway engineering to influence native and altered erythromycin production through <i>E. Coli</i> [J]. Metabolic engineering, 2013, 19: 42-49. [14]Chen, Xianzhong, et al. Metabolic engineering of <i>Escherichia coli</i>: A sustainable industrial platform for bio-based chemical production [J]. Biotechnology advances, 2013, 31.8: 1200-1223.<p></p>

---

Latest revision as of 17:44, 24 October 2014

pT7-RBS+loading module+KS-AT1+KR1+ACP+KS-AT2

Design Notes

Source

Saccharopolyspora erythraea

References

[1]Cane, David E. Programming of erythromycin biosynthesis by a modular polyketide synthase [J]. Journal of Biological Chemistry, 2010, 285.36: 27517-27523.

[2]Komaki, Hisayuki, et al. Genome based analysis of type-I polyketide synthase and nonribosomal peptide synthetase gene clusters in seven strains of five representative Nocardia species [J]. BMC genomics 15.1 (2014): 323.

[3]Pfeifer, Blaine A., et al. Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli [J]. Science, 2001, 291.5509: 1790-1792.

[4]Tae, Hongseok, Jae Kyung Sohng, and Kiejung Park. Development of an analysis program of type I polyketide synthase gene clusters using homology search and profile hidden Markov model [J]. Journal of microbiology and biotechnology, 2009, 19.2: 140-146.

[5]Cortes, Jesus, et al. An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea [J]. 1990: 176-178.

[6]Khosla, Chaitan, Shiven Kapur, and David E. Cane. Revisiting the modularity of modular polyketide synthases [J]. Current opinion in chemical biology, 2009, 13.2: 135-143.

[7]Menzella, Hugo G., et al. Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster [J]. Journal of Industrial Microbiology and Biotechnology,2006, 33.1: 22-28.

[8]Oliynyk, Markiyan, et al. A hybrid modular polyketide synthase obtained by domain swapping [J]. Chemistry & biology,1996, 3.10: 833-839.

[9]Lau, Janice, David E. Cane, and Chaitan Khosla. Substrate specificity of the loading didomain of the erythromycin polyketide synthase [J]. Biochemistry, 2000, 39.34: 10514-10520.

[10]Nowak-Thompson, Brian, et al. Characterization of the pyoluteorin biosynthetic gene cluster of Pseudomonas fluorescens Pf-5 [J]. Journal of bacteriology, 1999, 181.7: 2166-2174.

[11]Caffrey, Patrick, et al. Amphotericin biosynthesis in Streptomyces nodosus deductions from analysis of polyketide synthase and late genes [J]. Chemistry & biology,2001, 8.7: 713-723. [12]Dunn, Briana J., et al. Comparative analysis of the substrate specificity of trans-versus cis-acyltransferases of assembly line polyketide synthases [J]. Biochemistry,2014.

[13]Jiang, Ming, and Blaine A. Pfeifer. Metabolic and pathway engineering to influence native and altered erythromycin production through E. Coli [J]. Metabolic engineering, 2013, 19: 42-49. [14]Chen, Xianzhong, et al. Metabolic engineering of Escherichia coli: A sustainable industrial platform for bio-based chemical production [J]. Biotechnology advances, 2013, 31.8: 1200-1223.