Difference between revisions of "Part:BBa K1442041"

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−	This is the sequence for the MS2 hairpin (box)	+	The MS2 protein binding box is a highly specific RNA hairpin loop structure in viral RNA that binds the MS2 coat protein of the bacteriophage in order to allow encapsidation of the genome and represses the translational of replicase synthase [1]. <p> </p>
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		+	Isaacs et al [2] noted that the MS2 protein binding box is of use for engineering RNA transcriptional activators via the DNA-protein binding interactions and the hairpin has thus been shown that the MS2 box can be used to drive expression of proteins when localised to a promoter (e.g. the MS2 protein is fused to a DNA-binding protein and the MS2 box is localised to its target promoter, driving expression).
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Revision as of 18:58, 16 October 2014

MS2 bacteriophage protein binding box (hairpin)

The MS2 protein binding box is a highly specific RNA hairpin loop structure in viral RNA that binds the MS2 coat protein of the bacteriophage in order to allow encapsidation of the genome and represses the translational of replicase synthase [1].

Isaacs et al [2] noted that the MS2 protein binding box is of use for engineering RNA transcriptional activators via the DNA-protein binding interactions and the hairpin has thus been shown that the MS2 box can be used to drive expression of proteins when localised to a promoter (e.g. the MS2 protein is fused to a DNA-binding protein and the MS2 box is localised to its target promoter, driving expression).

Sequence and Features