Difference between revisions of "Part:BBa K1442039"
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<partinfo>BBa_K1442039 short</partinfo>
 
<partinfo>BBa_K1442039 short</partinfo>
  
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The self-cleaving 2A peptide derived from porcine teschovirus-1 is a coding region that has been utilised by viruses to self-cleave during translation and is speculated to have arisen to overcome traditional IRES sequences due to its much smaller coding length (an IRES is usually greater than 500 bases).  
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The self-cleaving 2A peptide is a virally derived coding region that has been utilised by viruses to self-cleave during translation and is likely to have arisen to overcome traditional IRES sequences due to its much smaller coding length (an IRES is usually greater than 500 bases) and allows for a smaller viral genome [1].
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Of the available 2A coding regions coding for the peptide from various viruses: foot-and-mouth disease virus, equine rhinitis A, <i>Thosea asigna</i>
  
 
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Revision as of 07:01, 16 October 2014

P2A self-cleaving peptide sequence

The self-cleaving 2A peptide is a virally derived coding region that has been utilised by viruses to self-cleave during translation and is likely to have arisen to overcome traditional IRES sequences due to its much smaller coding length (an IRES is usually greater than 500 bases) and allows for a smaller viral genome [1].

Of the available 2A coding regions coding for the peptide from various viruses: foot-and-mouth disease virus, equine rhinitis A, Thosea asigna

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]