Difference between revisions of "Part:BBa K1442039"

 
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<partinfo>BBa_K1442039 short</partinfo>
 
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The P2A RNA sequence causes translation to skip when the ribosome reads the sequence.
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The self-cleaving 2A peptide derived from porcine teschovirus-1 is a coding region that has been utilised by viruses to self-cleave during translation and is speculated to have arisen to overcome traditional IRES sequences due to its much smaller coding length (an IRES is usually greater than 500 bases).
  
 
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Revision as of 06:52, 16 October 2014

P2A self-cleaving peptide sequence

The self-cleaving 2A peptide derived from porcine teschovirus-1 is a coding region that has been utilised by viruses to self-cleave during translation and is speculated to have arisen to overcome traditional IRES sequences due to its much smaller coding length (an IRES is usually greater than 500 bases).

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]