Difference between revisions of "Part:BBa K1420001"
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<p>''merA'' is responsible for the detoxification of inorganic and organic mercury compounds. This enzyme is a mercury reductase that converts toxic forms of ionic mercury (Hg<sup>2+</sup>) to the less toxic form of volatile mercury (Hg<sup>0</sup>) in a NAD(P)H dependant reaction.</p>
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<p>''merA'' is a mercuric ion reductase that converts toxic forms of ionic mercury (Hg<sup>2+</sup>) to the less toxic form of volatile mercury (Hg<sup>0</sup>) in a NAD(P)H dependent reaction.
  
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<b>Structure</b>
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''Scheme 1.'' MerA Catalyzed Reaction
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[[File:MerA mechanism.JPG‎]]
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<b>Structure and Mechanism</b>
 
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Revision as of 18:23, 12 October 2014

merA, mercuric reductase from Serratia marcescens

Function

merA is a mercuric ion reductase that converts toxic forms of ionic mercury (Hg2+) to the less toxic form of volatile mercury (Hg0) in a NAD(P)H dependent reaction. Scheme 1. MerA Catalyzed Reaction <p>

MerA mechanism.JPG 

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Structure and Mechanism

Zone of Inhibition Results

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 1201
    Illegal NgoMIV site found at 1249
    Illegal NgoMIV site found at 1311
    Illegal NgoMIV site found at 1522
  • 1000
    COMPATIBLE WITH RFC[1000]