Difference between revisions of "Part:BBa K1420002"

Revision as of 23:33, 9 October 2014

merB, Organomercurial Lyase from Serratia marcescens

Function

The merB gene is often found immediately downstream of merA, and is essential for the detoxification and bioremediation of organic toxic mercury compounds in congruence with merA. The merB protein is a lyase that catalyzes the breaking of carbon-mercury bonds through protonolysis of toxic mercury compounds, such as methylmercury. This produces the less toxic and less mobile Hg²⁺ which is then completely volatilized to Hg⁰ when acted upon the enzyme merA.

Structure

Experimental Results

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
INCOMPATIBLE WITH RFC[25]
Illegal NgoMIV site found at 415
1000
COMPATIBLE WITH RFC[1000]

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 <partinfo>BBa_K1420002 short</partinfo>
-Demethylates organomerury.
+<b>Function</b>
+<p></p>
+<p></p>
+<p>The ''merB'' gene is often found immediately downstream of ''merA'', and is essential for the detoxification and bioremediation of organic toxic mercury compounds in congruence with ''merA''. The ''merB'' protein is a lyase that catalyzes the breaking of carbon-mercury bonds through protonolysis of toxic mercury compounds, such as methylmercury. This produces the less toxic and less mobile Hg<sup>2+</sup> which is then completely volatilized to Hg<sup>0</sup> when acted upon the enzyme ''merA''.</p>
+<b>Structure</b>
+<p></p>
+<p></p>
+<b>Experimental Results</b>
+<b></b>
 <!-- Add more about the biology of this part here
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-<span class='h3bb'>Sequence and Features</span>
+<b><span class='h3bb'>Sequence and Features</span></b>
 <partinfo>BBa_K1420002 SequenceAndFeatures</partinfo>