Difference between revisions of "Part:BBa K1202006"
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<partinfo>BBa_K1202006 short</partinfo> | <partinfo>BBa_K1202006 short</partinfo> | ||
| − | Trans Activator of Transcription (TAT) peptide is a special signal peptide that directs the attached proteins into eukaryotic cells in the extracellular matrix. This allow the transportation of desired proteins into the cells. The efficiency of the part can be manipulated by adding additional sequences such as HA2. | + | Trans Activator of Transcription (TAT) peptide is a special signal peptide that directs the attached proteins into eukaryotic cells in the extracellular matrix. The proteins conduct this kind of activity called "cell penetrating peptides" (CPP). |
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| + | This allow the transportation of desired proteins into the cells. The efficiency of the part can be manipulated by adding additional sequences such as HA2. | ||
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| + | In our project, we want to use this protein to direct our cancer killing protein "apoptin" into the colon cancer cells, efficiently. | ||
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Revision as of 23:34, 4 October 2013
TAT(Trans-Activator of Transcription) protein
Trans Activator of Transcription (TAT) peptide is a special signal peptide that directs the attached proteins into eukaryotic cells in the extracellular matrix. The proteins conduct this kind of activity called "cell penetrating peptides" (CPP).
This allow the transportation of desired proteins into the cells. The efficiency of the part can be manipulated by adding additional sequences such as HA2.
In our project, we want to use this protein to direct our cancer killing protein "apoptin" into the colon cancer cells, efficiently.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]