Difference between revisions of "Part:BBa K1071002"

 
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<partinfo>BBa_K1071002 short</partinfo>
 
<partinfo>BBa_K1071002 short</partinfo>
  
Gives resistance against the antibiotic chloramphenicol in eucaryotes.
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Chloramphenicol interacts with the 50s Subunit of bacterial ribosomes and blocks peptidyltransferase activity. The antibiotic is acting on gram negative as well as on gram positive bacteria. The enzyme Chloramphenicol acetyltransferase (CAT) transfers one or two Acetyl groups to the hydroxyl-Residues of Chloramphenicol. This inactivates the antibiotic.
  
 
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Revision as of 10:56, 29 September 2013

cat resistance (procaryotic)

Chloramphenicol interacts with the 50s Subunit of bacterial ribosomes and blocks peptidyltransferase activity. The antibiotic is acting on gram negative as well as on gram positive bacteria. The enzyme Chloramphenicol acetyltransferase (CAT) transfers one or two Acetyl groups to the hydroxyl-Residues of Chloramphenicol. This inactivates the antibiotic.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]