Difference between revisions of "Part:BBa K1228009"
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Human lysozyme (hLZ), the major protein in breast milk, exhibits microbicidal activity to various degrees against several bacterial strains. The HLH peptide(38Aminoacid peptides) and its N-terminal helix (H1) were the most potent bactericidal to bacteria. Evidence shows that HLH peptide and its N-terminal helix (H1) kill bacteria by crossing the outer membrane of Gram-negative bacteria via self-promoted uptake and is able to dissipate the membrane-potential-dependent respiration of Gram-positive bacteria. | Human lysozyme (hLZ), the major protein in breast milk, exhibits microbicidal activity to various degrees against several bacterial strains. The HLH peptide(38Aminoacid peptides) and its N-terminal helix (H1) were the most potent bactericidal to bacteria. Evidence shows that HLH peptide and its N-terminal helix (H1) kill bacteria by crossing the outer membrane of Gram-negative bacteria via self-promoted uptake and is able to dissipate the membrane-potential-dependent respiration of Gram-positive bacteria. | ||
Lactoferrin (Lf) is a multifunctional member of the transferrin. Lf is found at the mucosal surface where it functions as a prominent component of the first line of the host defense system against infection and inflammation. The protein(25Aminoacid peptides) is part of Lf.it has a broad spectrum of anti-infection and anti-inflammatory function. Also, lactoferrin has a broad anti-bacterial range and strong anti-bacterial activity. | Lactoferrin (Lf) is a multifunctional member of the transferrin. Lf is found at the mucosal surface where it functions as a prominent component of the first line of the host defense system against infection and inflammation. The protein(25Aminoacid peptides) is part of Lf.it has a broad spectrum of anti-infection and anti-inflammatory function. Also, lactoferrin has a broad anti-bacterial range and strong anti-bacterial activity. | ||
| − | 25 aminoacid peptides and 38 peptides are combined with Promoter veg(https://parts.igem.org/Part:BBa_K541503) and T1 terminator. This fusion protein may have much more strong anti-bacterial activity. | + | 25 aminoacid peptides and 38 aminoacid peptides are combined with Promoter veg(https://parts.igem.org/Part:BBa_K541503) and T1 terminator. This fusion protein may have much more strong anti-bacterial activity. |
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Revision as of 10:07, 27 September 2013
38aa and 25aa fusion peptide with T1 terminator and Constitutive promoter veg
Human lysozyme (hLZ), the major protein in breast milk, exhibits microbicidal activity to various degrees against several bacterial strains. The HLH peptide(38Aminoacid peptides) and its N-terminal helix (H1) were the most potent bactericidal to bacteria. Evidence shows that HLH peptide and its N-terminal helix (H1) kill bacteria by crossing the outer membrane of Gram-negative bacteria via self-promoted uptake and is able to dissipate the membrane-potential-dependent respiration of Gram-positive bacteria. Lactoferrin (Lf) is a multifunctional member of the transferrin. Lf is found at the mucosal surface where it functions as a prominent component of the first line of the host defense system against infection and inflammation. The protein(25Aminoacid peptides) is part of Lf.it has a broad spectrum of anti-infection and anti-inflammatory function. Also, lactoferrin has a broad anti-bacterial range and strong anti-bacterial activity. 25 aminoacid peptides and 38 aminoacid peptides are combined with Promoter veg(https://parts.igem.org/Part:BBa_K541503) and T1 terminator. This fusion protein may have much more strong anti-bacterial activity.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]