Difference between revisions of "Part:BBa K1119002"
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<partinfo>BBa_K1119002 short</partinfo>
 
<partinfo>BBa_K1119002 short</partinfo>
  
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aceA codes for isocitrate lyase, native in E. coli strain BW25113. They are enzymes involved in the glyoxylate cycle in plants and bacteria. This part is useful for regulating metabolic pathway.  
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aceA codes for isocitrate lyase, native in E. coli strain BW25113. This part is useful for regulating metabolic pathway. This is enzyme involved in the glyoxylate cycle in plants and bacteria. The glyoxylate enzyme allows plants and bacteria to use fatty acids as a substrate for gluconeogenesis and avoid complete oxiation into CO2. HKUST 2013 team has introduced this prokaryotic gene into mammalian cell to create an artificial futile cycle that increases uptake of fatty acids in the medium.  
  
 
<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here

Revision as of 08:51, 25 September 2013

aceA

aceA codes for isocitrate lyase, native in E. coli strain BW25113. This part is useful for regulating metabolic pathway. This is enzyme involved in the glyoxylate cycle in plants and bacteria. The glyoxylate enzyme allows plants and bacteria to use fatty acids as a substrate for gluconeogenesis and avoid complete oxiation into CO2. HKUST 2013 team has introduced this prokaryotic gene into mammalian cell to create an artificial futile cycle that increases uptake of fatty acids in the medium.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]