Difference between revisions of "AHL"

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acyl-homoserine lactones
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Full name: acyl-homoserine lactones<br/>
 
These are small signalling molecules which are employed in "quorum sensing" systems.<br>
 
These are small signalling molecules which are employed in "quorum sensing" systems.<br>
Currently, the most well studied of these molecules is 3-oxohexanoyl-homoserine lactone [[3OC6HSL]], which binds to the transcriptional activator protein LuxR to alter transcriptional regulation of the [[Help:Glossary:L#Lux_operon|Lux operon]]. <br>
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Currently, the most well studied of these molecules is 3-oxohexanoyl-homoserine lactone [[3OC6HSL]], which binds to the transcriptional activator protein LuxR to alter transcriptional regulation of the [[Lux|Lux operon]]. <br>
 
references:  
 
references:  
 
* Collins, C.H. et al. Directed Evolution of V. Fischeri LuxR for increased acyl-HSL's.  Molecular Microbiology.  2005. [http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2958.2004.04437.x Abstract]
 
* Collins, C.H. et al. Directed Evolution of V. Fischeri LuxR for increased acyl-HSL's.  Molecular Microbiology.  2005. [http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2958.2004.04437.x Abstract]

Revision as of 04:16, 13 June 2006

Full name: acyl-homoserine lactones
These are small signalling molecules which are employed in "quorum sensing" systems.
Currently, the most well studied of these molecules is 3-oxohexanoyl-homoserine lactone 3OC6HSL, which binds to the transcriptional activator protein LuxR to alter transcriptional regulation of the Lux operon.
references:

  • Collins, C.H. et al. Directed Evolution of V. Fischeri LuxR for increased acyl-HSL's. Molecular Microbiology. 2005. [http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2958.2004.04437.x Abstract]