Difference between revisions of "Part:BBa K847001"

 
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<partinfo>BBa_K847001 short</partinfo>
 
<partinfo>BBa_K847001 short</partinfo>
  
''Deinococcus radiodurans'' is an extremely radiation-resistant bacterium: while about 10 Gy (absorbed radiation dose, Gray) can kill most vertebrates, ''D. radiodurans'' can withstand up to 12,000 Gy. Current literature supports this finding with ''D. radiodurans’'' unique genetic makeup which allows it to better handle radiation exposure. The two main effects of radiation exposure to bacterial cells are DNA damage and the creation of toxic superoxide species (Daly 2009). Two DNA damage prevention and repair proteins in ''D. radiodurans'' have been shown to outperform analogs in less radiation-tolerant bacteria. By binding to DNA, the protein Dps-1 (DNA-binding proteins from starved cells) protects it from the reactive superoxide species formed by ionizing radiation (Slade and Miroslav 2011).  
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''Deinococcus radiodurans'' is an extremely radiation-resistant bacterium: while about 10 Gy (absorbed radiation dose, Gray) can kill most vertebrates, ''D. radiodurans'' can withstand up to 12,000 Gy. Current literature supports this finding with ''D. radiodurans’'' unique genetic makeup which allows it to better handle radiation exposure. The two main effects of radiation exposure to bacterial cells are DNA damage and the creation of toxic superoxide species (Daly 2009). Two DNA damage prevention and repair proteins in ''D. radiodurans'' have been shown to outperform analogs in less radiation-tolerant bacteria. By binding to DNA, the protein DpsG (DNA-binding proteins from starved cells) protects it from the reactive superoxide species formed by ionizing radiation (Slade and Miroslav 2011).  
  
  

Latest revision as of 02:43, 4 October 2012

''Deinococcus radiodurans'' DNA repair mechanism, DpsG

Deinococcus radiodurans is an extremely radiation-resistant bacterium: while about 10 Gy (absorbed radiation dose, Gray) can kill most vertebrates, D. radiodurans can withstand up to 12,000 Gy. Current literature supports this finding with D. radiodurans’ unique genetic makeup which allows it to better handle radiation exposure. The two main effects of radiation exposure to bacterial cells are DNA damage and the creation of toxic superoxide species (Daly 2009). Two DNA damage prevention and repair proteins in D. radiodurans have been shown to outperform analogs in less radiation-tolerant bacteria. By binding to DNA, the protein DpsG (DNA-binding proteins from starved cells) protects it from the reactive superoxide species formed by ionizing radiation (Slade and Miroslav 2011).


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]