Difference between revisions of "Part:BBa K861400"

Revision as of 12:06, 16 August 2012

For a E.coli to degrade fatty acid, at least four enzymes – FadA, FadB, FadD, FadE and transporter—FadL are needed. Long chain fatty acids(FAs) are firstly being imported by the transmembrane protein FadL. After FAs get into cells, they will be added a CoA by inner membrane-associated FadD (acyl-CoA synthase). β-oxidation is initiated by FadE(acyl-CoA dehydrogenase), which will convert acyl-CoA into enoyl-CoA. The followed cycles of hydration, oxidation, and thiolytic cleavage are carried out by tetrameric complex consisting of two FadA and two FadB proteins.

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
INCOMPATIBLE WITH RFC[21]
Illegal BglII site found at 84
Illegal BglII site found at 960
23
COMPATIBLE WITH RFC[23]
25
INCOMPATIBLE WITH RFC[25]
Illegal AgeI site found at 574
1000
COMPATIBLE WITH RFC[1000]

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 For a E.coli to degrade fatty acid, at least four enzymes – FadA, FadB, FadD, FadE and transporter—FadL are needed. Long chain fatty acids(FAs) are firstly being imported by the transmembrane protein FadL. After FAs get into cells, they will be added a CoA by inner membrane-associated FadD (acyl-CoA synthase). β-oxidation is initiated by FadE(acyl-CoA dehydrogenase), which will convert acyl-CoA into enoyl-CoA. The followed cycles of hydration, oxidation, and thiolytic cleavage are carried out by tetrameric complex consisting of two FadA and two FadB proteins.
 <partinfo>BBa_K861400 SequenceAndFeatures</partinfo>
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