Difference between revisions of "Part:BBa K524100"
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<partinfo>BBa_K524100 short</partinfo> | <partinfo>BBa_K524100 short</partinfo> | ||
| − | Bcr is a multidrug efflux pump that belongs to the major facilitator superfamily (MFS), native to ''Escherichia coli''. When overexpressed in ''E. coli'', it is known to confer varying degree of resistance to several antibiotics, including bicyclomycin (selection-capable); tetracycline (8-fold increase in MIC^); kanamycin (4-fold increase in MIC^); fosfomycin (4-fold increase in MIC^); and acriflavine (2-fold increase in MIC^). | + | Bcr is a multidrug efflux pump that belongs to the major facilitator superfamily (MFS), native to ''Escherichia coli''. When overexpressed in ''E. coli'', it is known to confer varying degree of resistance to several antibiotics, including bicyclomycin (selection-capable); tetracycline (8-fold increase in MIC^); kanamycin (4-fold increase in MIC^); fosfomycin (4-fold increase in MIC^); and acriflavine (2-fold increase in MIC^)[see Reference 2]. |
^: Compared with wild type | ^: Compared with wild type | ||
Revision as of 09:31, 2 October 2011
Bcr - multidrug efflux system
Bcr is a multidrug efflux pump that belongs to the major facilitator superfamily (MFS), native to Escherichia coli. When overexpressed in E. coli, it is known to confer varying degree of resistance to several antibiotics, including bicyclomycin (selection-capable); tetracycline (8-fold increase in MIC^); kanamycin (4-fold increase in MIC^); fosfomycin (4-fold increase in MIC^); and acriflavine (2-fold increase in MIC^)[see Reference 2].
^: Compared with wild type
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 503
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 99
- 1000COMPATIBLE WITH RFC[1000]