Difference between revisions of "Part:BBa K524100"
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<partinfo>BBa_K524100 short</partinfo>
 
<partinfo>BBa_K524100 short</partinfo>
  
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Bcr is a multidrug efflux pump that belongs to the major facilitator superfamily (MFS), native to Escherichia coli. When overexpressed in E. coli, it is known to confer varying degree of resistance to several antibiotics, including bicyclomycin (selection-capable); tetracycline (8-fold increase in MIC*); kanamycin (4-fold increase in MIC*); fosfomycin (4-fold increase in MIC*); and acriflavine (2-fold increase in MIC*).
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Bcr is a multidrug efflux pump that belongs to the major facilitator superfamily (MFS), native to Escherichia coli. When overexpressed in E. coli, it is known to confer varying degree of resistance to several antibiotics, including bicyclomycin (selection-capable); tetracycline (8-fold increase in MIC^); kanamycin (4-fold increase in MIC^); fosfomycin (4-fold increase in MIC^); and acriflavine (2-fold increase in MIC^).
  
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* - Compared with wild type
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^: Compared with wild type
  
 
<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here

Revision as of 13:31, 27 September 2011

Bcr - multidrug efflux system

Bcr is a multidrug efflux pump that belongs to the major facilitator superfamily (MFS), native to Escherichia coli. When overexpressed in E. coli, it is known to confer varying degree of resistance to several antibiotics, including bicyclomycin (selection-capable); tetracycline (8-fold increase in MIC^); kanamycin (4-fold increase in MIC^); fosfomycin (4-fold increase in MIC^); and acriflavine (2-fold increase in MIC^).

^: Compared with wild type

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BamHI site found at 503
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 99
  • 1000
    COMPATIBLE WITH RFC[1000]