Difference between revisions of "Part:BBa K554000"
Line 3: Line 3:
  
 
SoxS is a promoter regulated by the SoxR transcription factor, which is activated by NO. ''E. coli'' can naturally respond to redox signals through a superoxide stress system composed by SoxR gene, SoxS promoter and the genes associated with SoxS promoter. Thus, in the presence of NO, SoxR activates transcription of the gene regulated by SoxS promoter (Hidalgo et al, 1998). This promoter is used by UNICAMP-EMSE Brazil team in the NO sensor device (which senses NO levels and responds by producing and secreting IL-10.
 
SoxS is a promoter regulated by the SoxR transcription factor, which is activated by NO. ''E. coli'' can naturally respond to redox signals through a superoxide stress system composed by SoxR gene, SoxS promoter and the genes associated with SoxS promoter. Thus, in the presence of NO, SoxR activates transcription of the gene regulated by SoxS promoter (Hidalgo et al, 1998). This promoter is used by UNICAMP-EMSE Brazil team in the NO sensor device (which senses NO levels and responds by producing and secreting IL-10.
 +
  
 
<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here

Revision as of 18:52, 21 September 2011

SoxS promoter

SoxS is a promoter regulated by the SoxR transcription factor, which is activated by NO. E. coli can naturally respond to redox signals through a superoxide stress system composed by SoxR gene, SoxS promoter and the genes associated with SoxS promoter. Thus, in the presence of NO, SoxR activates transcription of the gene regulated by SoxS promoter (Hidalgo et al, 1998). This promoter is used by UNICAMP-EMSE Brazil team in the NO sensor device (which senses NO levels and responds by producing and secreting IL-10.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]



References

  1. Hidalgo E, Leautaud V, Demple B (1998) The redox-regulated SoxR protein acts from a single DNA site as a repressor and an allosteric activator. The EMBO Journal 17(9)2629–2636